Review



plasma fgf21 levels  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    R&D Systems plasma fgf21 levels
    Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for <t>FGF21</t> circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.
    Plasma Fgf21 Levels, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+fgf21+levels/Simple+Plex+Control+for+Human+FGF-21/med_rxiv__64898__2025__12__10__25342016-56-0-14
    Average 93 stars, based on 8 article reviews
    plasma fgf21 levels - by Bioz Stars, 2026-10
    93/100 stars

    Images

    1) Product Images from "Elevated FGF21 and triglycerides in SLC25A13 carriers support the G3P-ChREBP Citrin Deficiency disease hypothesis"

    Article Title: Elevated FGF21 and triglycerides in SLC25A13 carriers support the G3P-ChREBP Citrin Deficiency disease hypothesis

    Journal: medRxiv

    doi: 10.64898/2025.12.10.25342016

    Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for FGF21 circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.
    Figure Legend Snippet: Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for FGF21 circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.

    Techniques Used: Mutagenesis, Control, Clinical Proteomics

    (A) TGs were compared between the N = 7 control participants and the N =45 SLC25A13 mutation carriers for whom TG values were available in the TWB. These data show a nonsignificant TG increase in mutation carriers. (B) A plot of TGs as a function of FGF21 in mutation carriers shows a strong positive correlation (Pearson’s correlation R = 0.58) that is counter to the depression of TGs by genetically proxied FGF21 in the general population and consistent with elevation of FGF21 and lipogenic transcription by a potentiated ChREBP system in SLC25A13 carriers.
    Figure Legend Snippet: (A) TGs were compared between the N = 7 control participants and the N =45 SLC25A13 mutation carriers for whom TG values were available in the TWB. These data show a nonsignificant TG increase in mutation carriers. (B) A plot of TGs as a function of FGF21 in mutation carriers shows a strong positive correlation (Pearson’s correlation R = 0.58) that is counter to the depression of TGs by genetically proxied FGF21 in the general population and consistent with elevation of FGF21 and lipogenic transcription by a potentiated ChREBP system in SLC25A13 carriers.

    Techniques Used: Control, Mutagenesis

    Related Articles

    Clinical Proteomics:

    Article Title: Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
    Article Snippet: .. Plasma FGF21 levels were analyzed using an ELISA kit (MF2100; R&D Systems, Minneapolis, MN, USA) ( I). ..

    Article Title: Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
    Article Snippet: .. Plasma FGF21 levels were measured using mouse FGF21 Quantikine ELISA (R&D Systems). .. Plasma IGF-binding protein 2 (IGFBP2) levels were measured using mouse/rat IGFP2 ELISA kit (Mediagnost).

    Article Title: Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT.
    Article Snippet: Serum ALT levels were quantified using the transaminase CII-test Wako kit (Wako). .. Plasma FGF21 levels were determined using Mouse/Rat FGF-21 Quantikine ELISA Kit (R&D Systems). ..

    Enzyme-linked Immunosorbent Assay:

    Article Title: Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
    Article Snippet: .. Plasma FGF21 levels were analyzed using an ELISA kit (MF2100; R&D Systems, Minneapolis, MN, USA) ( I). ..

    Article Title: Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
    Article Snippet: .. Plasma FGF21 levels were measured using mouse FGF21 Quantikine ELISA (R&D Systems). .. Plasma IGF-binding protein 2 (IGFBP2) levels were measured using mouse/rat IGFP2 ELISA kit (Mediagnost).

    Article Title: Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT.
    Article Snippet: Serum ALT levels were quantified using the transaminase CII-test Wako kit (Wako). .. Plasma FGF21 levels were determined using Mouse/Rat FGF-21 Quantikine ELISA Kit (R&D Systems). ..



    Similar Products

    mouse/rat fgf-21 quantikine elisa kit  (Bio-Techne corporation)
    96
    Bio-Techne corporation mouse/rat fgf-21 quantikine elisa kit
    Mouse/Rat Fgf 21 Quantikine Elisa Kit, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+fgf21+levels/Mouse%2FRat+FGF-21+Quantikine+ELISA+Kit/bio-techne+corporation___mf2100
    Average 96 stars, based on 1 article reviews
    mouse/rat fgf-21 quantikine elisa kit - by Bioz Stars, 2026-10
    96/100 stars
    		  Buy from Supplier
    c plasma fgf21 protein levels  (Proteintech)
    93
    Proteintech c plasma fgf21 protein levels
    C Plasma Fgf21 Protein Levels, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+fgf21+levels/Mouse+FGF-21+ELISA+Kit/us12590307-1321-43-60
    Average 93 stars, based on 1 article reviews
    c plasma fgf21 protein levels - by Bioz Stars, 2026-10
    93/100 stars
    		  Buy from Supplier
    plasma fgf21 levels  (R&D Systems)
    93
    R&D Systems plasma fgf21 levels
    Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for <t>FGF21</t> circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.
    Plasma Fgf21 Levels, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+fgf21+levels/Simple+Plex+Control+for+Human+FGF-21/med_rxiv__64898__2025__12__10__25342016-56-0-14
    Average 93 stars, based on 1 article reviews
    plasma fgf21 levels - by Bioz Stars, 2026-10
    93/100 stars
    		  Buy from Supplier
    plasma fgf21 levels  (Cusabio)
    93
    Cusabio plasma fgf21 levels
    FIGURE 2 | Relative gene and protein expression of <t>FGF21</t> receptors and signaling pathways in vWAT. (A, B) Gene expression of FGFR1 and KLB. (C, D) Protein expression of phosphorylated/total Akt (Ser 473) and Erk1/2 (T202/204). *P < 0.05 vs. NGT group. Data were analyzed by a one-way ANOVA with Tukey post hoc test. NGT, n = 13; GDM-res, n = 17; GDM-dys, n = 9.
    Plasma Fgf21 Levels, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+fgf21+levels/FGF21/pm34912302-57-1-15
    Average 93 stars, based on 1 article reviews
    plasma fgf21 levels - by Bioz Stars, 2026-10
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for FGF21 circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.

    Journal: medRxiv

    Article Title: Elevated FGF21 and triglycerides in SLC25A13 carriers support the G3P-ChREBP Citrin Deficiency disease hypothesis

    doi: 10.64898/2025.12.10.25342016

    Figure Lengend Snippet: Age and ex-matched SLC25A13 mutation carriers from the TWB were assayed for FGF21 circulation and urinary sodium. The data show that male (A) and female (B) mutation carriers have higher levels of FGF21 than control participants and that male and female mutation carriers have higher levels of urinary sodium (C) than control participants. Further, female CD patients have much higher levels of circulating FGF21 than control female age-matched participants (D). (A) Plasma FGF21 levels (N = 25 per group); (B) Plasma FGF21 levels (N = 27 controls, N = 25 carriers); (C) urinary sodium (N = 48 controls, N = 49 carriers); (D) plasma FGF21 (N = 10 controls, N = 2 CD). Symbols: □ male controls; ■ male carriers; ○ female controls; ● female carriers; ● female CD patients. P values are from Student’s t-test.

    Article Snippet: Plasma FGF21 levels were quantified in duplicate using the Quantikine® Human FGF-21 ELISA kit (R&D Systems, DF2100) according to the manufacturer’s protocol.

    Techniques: Mutagenesis, Control, Clinical Proteomics

    (A) TGs were compared between the N = 7 control participants and the N =45 SLC25A13 mutation carriers for whom TG values were available in the TWB. These data show a nonsignificant TG increase in mutation carriers. (B) A plot of TGs as a function of FGF21 in mutation carriers shows a strong positive correlation (Pearson’s correlation R = 0.58) that is counter to the depression of TGs by genetically proxied FGF21 in the general population and consistent with elevation of FGF21 and lipogenic transcription by a potentiated ChREBP system in SLC25A13 carriers.

    Journal: medRxiv

    Article Title: Elevated FGF21 and triglycerides in SLC25A13 carriers support the G3P-ChREBP Citrin Deficiency disease hypothesis

    doi: 10.64898/2025.12.10.25342016

    Figure Lengend Snippet: (A) TGs were compared between the N = 7 control participants and the N =45 SLC25A13 mutation carriers for whom TG values were available in the TWB. These data show a nonsignificant TG increase in mutation carriers. (B) A plot of TGs as a function of FGF21 in mutation carriers shows a strong positive correlation (Pearson’s correlation R = 0.58) that is counter to the depression of TGs by genetically proxied FGF21 in the general population and consistent with elevation of FGF21 and lipogenic transcription by a potentiated ChREBP system in SLC25A13 carriers.

    Article Snippet: Plasma FGF21 levels were quantified in duplicate using the Quantikine® Human FGF-21 ELISA kit (R&D Systems, DF2100) according to the manufacturer’s protocol.

    Techniques: Control, Mutagenesis

    FIGURE 2 | Relative gene and protein expression of FGF21 receptors and signaling pathways in vWAT. (A, B) Gene expression of FGFR1 and KLB. (C, D) Protein expression of phosphorylated/total Akt (Ser 473) and Erk1/2 (T202/204). *P < 0.05 vs. NGT group. Data were analyzed by a one-way ANOVA with Tukey post hoc test. NGT, n = 13; GDM-res, n = 17; GDM-dys, n = 9.

    Journal: Frontiers in endocrinology

    Article Title: Association of Elevated Plasma FGF21 and Activated FGF21 Signaling in Visceral White Adipose Tissue and Improved Insulin Sensitivity in Gestational Diabetes Mellitus Subtype: A Case-Control Study.

    doi: 10.3389/fendo.2021.795520

    Figure Lengend Snippet: FIGURE 2 | Relative gene and protein expression of FGF21 receptors and signaling pathways in vWAT. (A, B) Gene expression of FGFR1 and KLB. (C, D) Protein expression of phosphorylated/total Akt (Ser 473) and Erk1/2 (T202/204). *P < 0.05 vs. NGT group. Data were analyzed by a one-way ANOVA with Tukey post hoc test. NGT, n = 13; GDM-res, n = 17; GDM-dys, n = 9.

    Article Snippet: The plasma FGF21 levels at delivery were tested via a purchasable ELISA kit (CSB-E16844 h, Cusabio Biotech, Wuhan, China).

    Techniques: Expressing, Protein-Protein interactions, Gene Expression

    FIGURE 4 | Hypothesis on the role of FGF21 signaling in the visceral white adipose tissue (vWAT). The improved insulin sensitivity in women of the GDM-resistance group may be associated with the increased plasma FGF21 level and activated FGF21 signaling in vWAT.

    Journal: Frontiers in endocrinology

    Article Title: Association of Elevated Plasma FGF21 and Activated FGF21 Signaling in Visceral White Adipose Tissue and Improved Insulin Sensitivity in Gestational Diabetes Mellitus Subtype: A Case-Control Study.

    doi: 10.3389/fendo.2021.795520

    Figure Lengend Snippet: FIGURE 4 | Hypothesis on the role of FGF21 signaling in the visceral white adipose tissue (vWAT). The improved insulin sensitivity in women of the GDM-resistance group may be associated with the increased plasma FGF21 level and activated FGF21 signaling in vWAT.

    Article Snippet: The plasma FGF21 levels at delivery were tested via a purchasable ELISA kit (CSB-E16844 h, Cusabio Biotech, Wuhan, China).

    Techniques: Clinical Proteomics